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greatescape · 15-10-2010, 01:31 PM

qui pero c'e' uno studio del 2010 sull'arginina e il consumo di o2

Acute L-arginine supplementation reduces the O2 co... [J Appl Physiol. 2010] - PubMed result

Acute L-arginine supplementation reduces the O2 cost of moderate-intensity exercise and enhances high-intensity exercise tolerance.
Bailey SJ, Winyard PG, Vanhatalo A, Blackwell JR, Dimenna FJ, Wilkerson DP, Jones AM.

1Exeter University.
Abstract
It has recently been reported that dietary nitrate supplementation which increases plasma nitrite concentration, a biomarker of nitric oxide (NO) availability, improves exercise efficiency and exercise tolerance in healthy humans. We hypothesised that dietary supplementation with L-arginine, the substrate for nitric oxide synthase (NOS), would elicit similar responses. In a double-blind, crossover study, nine healthy males (aged 19-38 years) consumed a 500 mL beverage containing 6 g of L-arginine (ARG) or a placebo beverage (PLA), and completed a series of 'step' moderate-intensity and severe-intensity exercise bouts 1 h post-ingestion. Plasma [nitrite] was significantly greater following L-arginine consumption compared to placebo (ARG: 331 +/- 198 vs. PLA: 159 +/- 102 nM; P<0.05) and systolic blood pressure was significantly reduced (ARG: 123 +/- 3 vs. PLA: 131 +/- 5 mmHg; P<0.01). The steady-state VO(2) during moderate-intensity exercise was reduced by 7% in the ARG condition (ARG: 1.48 +/- 0.12 vs. PLA: 1.59 +/- 0.14 L*min(-1); P<0.05). During severe-intensity exercise, the VO(2) slow component amplitude was reduced (ARG: 0.58 +/- 0.23 vs. PLA: 0.76 +/- 0.29 L*min(-1); P<0.05) and the time-to-exhaustion was extended (ARG: 707 +/- 232 s vs. PLA: 562 +/- 145 s; P<0.05) following ARG. In conclusion, similar to the effects of increased dietary nitrate intake, elevating NO bioavailability through dietary L-arginine supplementation reduced the O(2) cost of moderate-intensity exercise and blunted the VO(2) slow component and extended the time-to-exhaustion during severe-intensity exercise.

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greatescape All the Truth Member Messaggi: 20,462 Data registrazione: Jun 2007	15-10-2010, 01:31 PM qui pero c'e' uno studio del 2010 sull'arginina e il consumo di o2 Acute L-arginine supplementation reduces the O2 co... [J Appl Physiol. 2010] - PubMed result Acute L-arginine supplementation reduces the O2 cost of moderate-intensity exercise and enhances high-intensity exercise tolerance. Bailey SJ, Winyard PG, Vanhatalo A, Blackwell JR, Dimenna FJ, Wilkerson DP, Jones AM. 1Exeter University. Abstract It has recently been reported that dietary nitrate supplementation which increases plasma nitrite concentration, a biomarker of nitric oxide (NO) availability, improves exercise efficiency and exercise tolerance in healthy humans. We hypothesised that dietary supplementation with L-arginine, the substrate for nitric oxide synthase (NOS), would elicit similar responses. In a double-blind, crossover study, nine healthy males (aged 19-38 years) consumed a 500 mL beverage containing 6 g of L-arginine (ARG) or a placebo beverage (PLA), and completed a series of 'step' moderate-intensity and severe-intensity exercise bouts 1 h post-ingestion. Plasma [nitrite] was significantly greater following L-arginine consumption compared to placebo (ARG: 331 +/- 198 vs. PLA: 159 +/- 102 nM; P<0.05) and systolic blood pressure was significantly reduced (ARG: 123 +/- 3 vs. PLA: 131 +/- 5 mmHg; P<0.01). The steady-state VO(2) during moderate-intensity exercise was reduced by 7% in the ARG condition (ARG: 1.48 +/- 0.12 vs. PLA: 1.59 +/- 0.14 Lmin(-1); P<0.05). During severe-intensity exercise, the VO(2) slow component amplitude was reduced (ARG: 0.58 +/- 0.23 vs. PLA: 0.76 +/- 0.29 Lmin(-1); P<0.05) and the time-to-exhaustion was extended (ARG: 707 +/- 232 s vs. PLA: 562 +/- 145 s; P<0.05) following ARG. In conclusion, similar to the effects of increased dietary nitrate intake, elevating NO bioavailability through dietary L-arginine supplementation reduced the O(2) cost of moderate-intensity exercise and blunted the VO(2) slow component and extended the time-to-exhaustion during severe-intensity exercise.