No bomb e PDE-5 inhibition

[mistersalvo]

Amount Per Serving % Daily Value

Folate (As NitroFolate [Folic Acid And Calcium Folinate]) 600mcg %

GlycoCarn® (Glycine Propionyl-L-Carnitine) 4.5g

KNO3 Nitrite-NO Technology And NOSA (Nitric Oxide Sustaining Agents) 273mg
K-NOx™ (Beta Vulgaris Extract (Root)), Grape Seed Extract (95% Proanthocyanidins), Pine Bark Extract (85% Proanthocyanidins, Butea Superba (Root), Glycyrrhiza Uralensis (Root), Forsythia Suspensa Extract (Fruit), AstaReal® (Astaxanthin) And Schizonepeta Tenuifolia Extract (Aerial Parts)


quali di questi elementi dovrebbe essere un pde5 inibitor??
ho letto che cialis e viagra lavorano in questo modo...inibendo il pde5...

[mistersalvo]

Phosphodiesterase type-5 (PDE-5) inhibitors are a new class of vasoactive drugs that have been developed for treatment of erectile dysfunction (ED). The mechanism of action involves active inhibition of the PDE-5 enzyme and resulting increase in cyclic guanosine monophosphate (cGMP) and smooth muscle relaxation in the penis. Sildenafil citrate (Viagra) is a potent and selective PDE-5 inhibitor, which is the first drug in this class to be approved for treatment of ED. More than 10 million men worldwide have been treated with this drug. Sildenafil has been shown to be generally effective in the treatment of ED, although the degree of efficacy varies according to the etiology and severity of the disorder. The drug is well tolerated, with relatively few contraindications (e.g., nitrates) and safety risks. The cardiovascular effects of sildenafil, in particular, have been extensively investigated. The results of recent studies suggest that sildenafil may have an additional role in the treatment of other male and female sexual disorders, such as premature ejaculation and female sexual arousal disorder, although results to date are inconclusive. Two additional agents in this class (tadalafil [Cialis], vardenafil [Levitra]) have been developed recently and are under regulatory review. Tadalafil is a long-acting PDE-5 inhibitor, which is effective for up to 36 hr in the majority of men. Vardenafil has a similar duration of action to sildenafil, but is more potent and selective biochemically. Both drugs appear to be generally safe and well tolerated, with a similar side-effect profile to sildenafil. There are no controlled comparison studies to date. Despite the overall effectiveness of PDE-5 inhibitors in the treatment of ED, significant psychological and interpersonal issues need to be addressed in their clinical use. The potential impact on societal attitudes toward sexuality and sexual dysfunction also warrants consideration.

[mistersalvo]

up

[greatescape]

icariin è un inibitore

[greatescape]

in questo integratore è l'axstantina o 3,3'-dihydroxy-ß-carotene-4,4'-dione

[xbit]

Originariamente inviato da greatescape

icariin è un inibitore

davvero ? blando .. o significante ?

[novellino]

Potent inhibition of human phosphodiesterase-5 by ... [J Nat Prod. 2008] - PubMed result

[novellino]

quello di prima era l'abstract ,questo lo studio completo .
ACS Publications - Cookie absent

[greatescape]

rivedendolo è l'insieme di questi
K-NOx™ (Beta Vulgaris Extract (Root)), Grape Seed Extract (95% Proanthocyanidins), Pine Bark Extract (85% Proanthocyanidins, Butea Superba (Root), Glycyrrhiza Uralensis (Root), Forsythia Suspensa Extract (Fruit), AstaReal® (Astaxanthin) And Schizonepeta Tenuifolia Extract (Aerial Parts)
che intervengono nell'inibizione del pde-5 in maniere diverse

[mistersalvo]

e questi singoli elementi si trovano??

[mistersalvo]

quindi oltre l'iicarin e la caffeina quali sn le sostanze che inibiscono la pde-5????????????

io ho letto che l'iicarin la dovrebbe inibire attorno al 10%...